The case studies reflect different products and processes at different stages, including mature products (where manufacturing optimisation is the key and where benefits can be realised within the project timeframe) and new product development (where quality, manufacturability, digital characterisation and customisation together with linking process parameters with product quality without extensive experimentation are the key).
In toto the case studies demonstrate both the use of generic digital design workflows, modelling frameworks and data-driven or mechanistic-based tools developed by the consortium to allow non-confidential feedback to be provided for continuous improvement of the digital design approach, and specific development of new modelling tools that exemplify the exploitation of the digital design approach in solving drug product and process development or commercial manufacturing problems.