The ADDoPT project's major showcase event, held on 28th March 2019 at the Clayton Hotel, Chiswick, London provided a vivid demonstration of the range of industry-ready new models, tools and approaches for digital design and operation of drug manufacturing processes and product performance arising from this major UK collaborative project.
Aligned with and preceding the Made Smarter report, the ADDoPT consortium partners have over the last four years been working across the pharmaceutical value chain to define and populate an Industry 4.0 framework for top-down, knowledge-driven digital design of drug products and digital design and operation of their manufacturing processes (smart manufacturing), and to identify and develop supporting modelling approaches.
Bringing together a wide range of mechanistic, statistical and hybrid predictive models and insight from industrial case studies applying them at four major pharmaceutical companies, the ADDoPT Digital Design Showcase exemplified business benefits including:
The packed programme included working demonstrations of new tools bringing together best in class predictive science and data analytic approaches to create digital twins of manufacturing processes and products, how these are being used in systems-based approaches linking molecular and material properties with process and product performance. and an outline of the transformational opportunities of Industrial Digitalisation for the pharmaceutical value chain (including CROs and CMOs) and for anyone involved in the formulation-based process industries.