In developing a conceptual systems framework linking all the tasks in the workflow from a molecule to a drug dosage form, our focus is on small molecules and oral solid dosage forms in order to identify the weakest links in the system and to facilitate switching between tools for certain tasks (for example switching from a purely experimental approach to a modelling - digital design - approach requiring fewer experiments and providing better predictive capability).
Moving from concepts into practice, WP1 also seeks to enhance existing computer implementations of system frameworks, including but not limited to PSE’s gCRYSTAL, gSOLIDS and gCOAS products.